Multipotent stem cells from adult olfactory mucosa
نویسندگان
چکیده
منابع مشابه
Multipotent adult stem cells
Catherine Verfaillie et al., have filed a patent for a stem cell found in the bone marrow of adults that can develop into every single tissue type in the body. It was thought until now that only embryonic stem cells were able to do this, but experiments detailed in the patent show that the cells, dubbed multipotent adult progenitor cells (MACPs) have the potential to do this. (Patent WO0111011,...
متن کاملStem cells and their niche in the adult olfactory mucosa.
It is well known that new neurons are produced in the adult brain, in the hippocampus and in the subventricular zone. The neural progenitors formed in the subventricular zone migrate forward and join in neural circuits as interneurons in the olfactory bulb, the target for axons from the olfactory sensory neurons in the nose. These neurons are also continually replaced during adulthood from a st...
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The discovery of stem cells in the adult human brain has revealed new possible scenarios for treatment of the sick or injured brain. Both clinical use of and preclinical research on human adult neural stem cells have, however, been seriously hampered by the fact that it has been impossible to passage these cells more than a very few times and with little expansion of cell numbers. Having explor...
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OBJECTIVE To characterize mesenchymal stem cells (MSCs) from human synovial membrane (SM). METHODS Cell populations were enzymatically released from the SM obtained from knee joints of adult human donors and were expanded in monolayer with serial passages at confluence. Cell clones were obtained by limiting dilution. At different passages, SM-derived cells were subjected to in vitro assays to...
متن کاملMultipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents.
The lateral walls of the forebrain lateral ventricles are the richest source of stem cells in the adult mammalian brain. These stem cells give rise to new olfactory neurons that are renewed throughout life. The neurons originate in the subventricular zone (SVZ), migrate within the rostral extension (RE) of the SVZ along the rostral migratory stream (RMS) within tube-like structures formed of gl...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2005
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.20360